Propofol bolus¶
Propofol bolus (clinical table).
| Name in the dataset | intraop_ppf |
| Type | clinical |
| Stored in | clinical_data.csv |
| Unit | mg |
Description¶
Single weight-based induction dose written as a preferred value. Zero in 3,719 of 6,043 GAs (TIVA is on the pump tracks, not here).
Measurement space¶
Vertical slices through the measurement space: how the true value is spread around a recorded one, for 4 recorded values chosen to show the different cases. Each panel has its own scale. Each is averaged over every record with that value in the release, from the pinned model; groups of fewer than 20 records are not shown.
- 100 mg (the commonest recorded value; 749 records): mean +1.99 mg, SD 8.15 mg, 95% between -19.1 and +19.3. Rounding: preferred values 60%, 50 mg 33%, 10 mg (base) 7%.
- 150 mg (the widest; 335 records): mean +5.17 mg, SD 29.9 mg, 95% between -23.5 and +75.9. Rounding: preferred values 76%, 50 mg 21%, 10 mg (base) 3%.
- 80 mg (the narrowest; 185 records): mean +0.537 mg, SD 2.9 mg, 95% between -6.67 and +3.9. Rounding: preferred values 84%, 10 mg (base) 16%.
- 50 mg (unlike the others; 25 records): mean +13.6 mg, SD 9.66 mg, 95% between -10.9 and +24.3. Rounding: 50 mg 92%, 10 mg (base) 8%.
Time¶
This variable carries no time of its own in the dataset.
Value¶
| Model kind | model: fitted rounding model (value kind); posterior over the true value |
| Resolution | heaped: a mixture of rounding modes (see the value model) |
| Status | measured |
| Studies | Rounding and heaping of propofol bolus |
In this release¶
How wide the true-value distribution is, record by record, over 2,335 of 6,388 records (all clinical rows) that have one. Computed with the pinned model, aggregates only.
| Median | p10 to p90 | |
|---|---|---|
| Standard deviation | 6.71 mg | 2.83 to 26.5 mg |
| 95% interval width | 23.3 mg | 9.44 to 88.3 mg |
| Mean minus recorded | 0.879 mg | -1.21 to 5.25 mg |
Value model¶
Model file: …/models/intraop_ppf.model.json. Read from the pinned snapshot of vitaldb-resolution at commit bb03ddfc8a (2026-10-18).
How a true value becomes the recorded one. The rules are tried in order: a record not taken by an earlier rule is taken by this one with the probability shown (where its condition holds); the last rule takes the rest. With no conditions, the shares follow directly.
| Order | Rule | Rounds to | Probability if reached | Share of records |
|---|---|---|---|---|
| 1 | preferred values | nearest | 72.1 % | 72.1 % |
| 2 | 50 mg | 50 mg (nearest) | 52.6 % | 14.7 % |
| 3 | 10 mg (base) | 10 mg (nearest) | the rest | 13.2 % |
- preferred values: nearest member of the set; values beyond the ends snap to 60 or 150
| Recorded resolution | 1 (modelled at 10) |
| True-value density | log_student_t_regression |
| Covariates | weight, age, sex |
| Fitted on | 2,328 records (VitalDB clinical_data.csv (intraop_ppf), non-zero values on the 10 mg grid with weight, age and sex) |
| BIC | 7,757 |
| Fitted | 2026-10-13 |
- Only 4 of 2,335 non-zero values are off the 10 mg grid; flagged off_grid.
Studies¶
| Study | Date | Status | Summary |
|---|---|---|---|
| Rounding and heaping of propofol bolus | 2026-10-13 | current | Recorded propofol bolus is a mixture of 3 rounding modes (preferred values, 50 mg, 10 mg (base)); the model gives the true value's distribution for each record. |
Worked examples¶
| Example | Side | Status | Summary |
|---|---|---|---|
| Charted propofol dose against the infusion pump | value | planned | The charted propofol bolus total against the volume the Orchestra pump records, as a check of the propofol heaping model and as a dose in mg/kg with its uncertainty. |
Figures¶
Tags: generated, vitaldb-resolution